Using precise word timing information improves decoding accuracy in a multiband-accelerated multimodal reading experiment
Abstract
The blood oxygen level dependent (BOLD) signal measured in fMRI experiments is generally regarded as sluggish and poorly suited for probing neural function at the rapid timescales involved in sentence comprehension. However, recent studies have shown the value of acquiring data with very short repetition times (TRs), not merely in terms of improvements in CNR through averaging, but also in terms of additional fine-grained temporal information. Using multiband-accelerated fMRI, we achieved whole-brain scans at 3mm resolution with a TR of just 500 ms at both 3T and 7T field strengths. This enabled sampling at close to the reading rate of one word per TR. By taking advantage of word timing information, we found that word decoding accuracy across two separate sets of scan sessions improved significantly with better overall performance at 7T than at 3T. The effect of TR was also investigated; we found that substantial word timing information can be extracted using fast TRs, with diminishing benefits beyond TRs of 1000 ms.
Keywords
Bibtex entry:
@article{vu2016using,
abstract = {The blood oxygen level dependent (BOLD) signal measured in fMRI experiments is generally regarded as sluggish and poorly suited for probing neural function at the rapid timescales involved in sentence comprehension. However, recent studies have shown the value of acquiring data with very short repetition times (TRs), not merely in terms of improvements in CNR through averaging, but also in terms of additional fine-grained temporal information. Using multiband-accelerated fMRI, we achieved whole-brain scans at 3mm resolution with a TR of just 500 ms at both 3T and 7T field strengths. This enabled sampling at close to the reading rate of one word per TR. By taking advantage of word timing information, we found that word decoding accuracy across two separate sets of scan sessions improved significantly with better overall performance at 7T than at 3T. The effect of TR was also investigated; we found that substantial word timing information can be extracted using fast TRs, with diminishing benefits beyond TRs of 1000 ms.},
author = {Vu, An T and Phillips, J.S. and Kay, K. and Phillips, M.E. and Johnson, M.R. and Shinkareva, S.V. and Tubridy, S. and Millin, R. and Grossman, M. and Gureckis, T.M. and others},
journal = {Cognitive neuropsychology},
number = {3-4},
pages = {265--275},
publisher = {Routledge},
title = {Using precise word timing information improves decoding accuracy in a multiband-accelerated multimodal reading experiment},
volume = {33},
year = {2016}}QR Code:
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